Symbol
Name
ID

Esr1
estrogen receptor 1 (alpha)
MGI:1352467

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

decreased thymus weight

thymus hypoplasia

decreased thymocyte number

abnormal thymus physiology

abnormal B cell differentiation

abnormal class switch recombination

decreased immature B cell number

increased double-positive T cell number

abnormal B cell number

decreased mature B cell number

increased plasma cell number

decreased B cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

increased osteoclast cell number

increased spleen germinal center number

abnormal immunoglobulin level

increased IgG3 level

abnormal osteoclast physiology

abnormal lymph node cell ratio

abnormal spleen physiology

increased anti-double stranded DNA antibody level

spermatic granuloma

glomerulonephritis

Availability

Mouse Genotype

Esr1^tm1.1Mma/Esr1^tm1.1Mma

Esr1^tm1.1Ohl/Esr1^tm1.1Ohl

Esr1^tm1Arnal/Esr1^tm1Arnal

Esr1^tm1Ksk/Esr1^tm1Ksk

Esr1^tm1.1Lja/Esr1^tm1.1Mma

Esr1^tm1.1Scma/Esr1^tm1.1Scma
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Ctsk^tm1(cre)Ska/Ctsk⁺
Esr1^tm1Mma/Esr1^tm1Mma (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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